An lipid status. J Clin Endocrinol Metab. 2003; 88:5444451. [PubMed: 14602787] 38. Lowell BB, Shulman GI. Mitochondrial dysfunction and sort 2 diabetes. Science. 2005; 307:384387. [PubMed: 15662004]NIHPA Author Manuscript NIHPA Author Manuscript NIHPA Author ManuscriptAtherosclerosis. Author manuscript; offered in PMC 2014 Could 01.Subash Shantha et al.PageHighlights Blood lactate is associated with atherosclerosis measured applying carotid MRI The association is robust and independent of other cardiovascular threat things Mitochondrial dysfunction mediates the function of insulin resistance on atherosclerosisNIHPA Author Manuscript NIHPA Author Manuscript NIHPA Author ManuscriptAtherosclerosis. Author manuscript; obtainable in PMC 2014 May possibly 01.Subash Shantha et al.PageNIHPA Author Manuscript NIHPA Author Manuscript NIHPA Author ManuscriptAtherosclerosis. Author manuscript; readily available in PMC 2014 May perhaps 01.Figure 1. MR angiogram as a scout imageImage is with the CCAs of a 71 yearold male ARIC Carotid MRI participant (Participant ID is J290624). Magnetic Resonance angiogram displaying scout film: a, b: the red line indicates a reference land mark 15 mm below the carotid bifurcation where the MRI variable maximum wall thickness was measured. Additional, c, d, e, f represents crosssectional images from the carotid wall at the reference line depicted inside a, b where maximum wall thickness was measured.TableDemographic and laboratory characteristics in the study participantsOverall (n = 1496)(trend)Traits five.9 (n = 378) 70.four (70.00.7) 51.0 19.eight 19.0 167.3 (160 183) 80.8 (69 110) 28.eight (28.59.1) 36.0 one hundred.9 (one hundred.101.7) 22 125.5 [114 139] 66.five [60 73] two.0 [1.1 11.7] 20.six 5.6 [5.four 7.1] 106.9 (105.508.3) 192.0 [165 219] 121 [92 163] 50.3 (49.41.2) 131 [9484] two.79 [1.75.31] 1.98 [1.40.10] 107 [8247] 54.two (52.26.1) 105 [87 130] 116 [95 136] 50.four (48.72.1) 121 [9067] 2.Price of 154775-43-6 53 [1.64.82] 195.9 [168 223] 193.3 [165 217] 101.8 (99.004.7) 104.0 (101.606.four) 5.five [5.three six.5] five.six [5.three six.9] 13.2 16.5 21.2 5.six [5.4 7.2] 106.two (104.909.5) 191.eight [162 230] 139 [96 49] 48.9 (47.20.six) 139 [10286] 3.05 [1.87.49] 2.0 [1.1 11.1] two.0 [1.1 11.0] 1.eight [1.1 four.1] 65.Formula of 6-(tert-Butoxy)-6-oxohexanoic acid 8 [61 72] 66.PMID:33449302 2 [61 75] 66.8 [63 74] 127.9 [113 138] 125.four [112 139] 127.7 [114 138] 16 18 22 97.two (95.49.0) one hundred.7 (99.102.3) one hundred.9 (99.502.3) 29.0 32.8 34.3 48.0 105.2 (103.207.1) 24 128.two [110 140] 66.7 [64 75] 3.0 [0.9 12.4] 31.9 5.eight [5.4 7.3] 116.8 (112.219.three) 195.9 [166 229] 143 [100 160] 47.7 (45.89.7) 174 [11732] three.81 [2.30.85] 27.9 (27.28.five) 28.five (28.09.1) 28.7 (28.29.two) 30.four (29.71.1) 77.four (67 102) 80 (65 98) 87 (73 104) 90 (81 117) 166.9 (160 182) 167.3 (160 182) 167.two (159 184) 167.eight (160 183) 0.104 0.021 0.001 0.001 0.001 0.001 0.157 0.128 0.113 0.001 0.112 0.001 0.168 0.017 0.001 0.001 0.001 17.1 18.9 22.9 20.2 0.126 13.0 18.1 19.5 28.0 0.001 56.two 49.two 50.four 50.six 0.134 70.four (69.50.9) 70.9 (70.01.3) 70.2 (69.60.8) 70.1 (69.71.1) 0.844 5.9.2 (n = 408) 7.3.1 (n=317) 9.two (n = 393)Subash Shantha et al.Lactate quartile unitsAge (years)Female ( )African American ( )Present smoking ( )Height (cms)Weight (Kgs)BMI (kg/m2)Obese ( 30kg/m2) ( )Waist circumference (cms)Hypertension ( )Systolic Blood Pressure (mmhg)Diastolic blood pressure (mmhg)HsCRP (mg/l)Sort two diabetics ( )HbA1C ( )Glucose (mg/dl)Total Cholesterol (mg/dl)Atherosclerosis. Author manuscript; available in PMC 2014 Could 01.LDL (mg/dl)HDL (mg/dl)Triglycerides (mg/dl)Trig/HDL ratioResults displayed as percentages, signifies (95 CIs) and medians [IQRs].Ptrend requires into account.