Product Name :
PRDM14 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
MGC59730 antibody PFM 11 antibody PFM11 antibody PR domain containing 14 antibody PR domain zinc finger protein 14 antibody PR domain-containing protein 14 antibody PRD14_HUMAN antibody PRDM 14 antibody PRDM14 antibody
Function :
PR domain zinc finger protein 14 is a transcription factor that has both positive and negative roles on transcription. It is expressed in embryonic stem cells and tends to be overexpressed in breast cancer. PRDM14 is required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells.800401-68-7 custom synthesis It may play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression.Formula of 4-(6-Bromopyridin-3-yl)morpholine PRDM14 directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human PRDM14 aa 1-250 / 571.
Species reactivity:
Human
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3073253
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33615661 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
~64kDa
Positive control :
Human embryonic stem cells, human lung, MCF-7