Product Name :
Smad2 Mouse Monoclonal Antibody [C9-B0]
Predicted band size :
Observed band size :
Synonyms:
Drosophila, homolog of, MADR2 antibody hMAD-2 antibody HsMAD2 antibody JV18 antibody JV18-1 antibody JV181 antibody MAD antibody MAD homolog 2 antibody MAD Related Protein 2 antibody Mad-related protein 2 antibody 展开
Function :
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein within Human Smad2 aa 151-450 / 467.(E)-But-2-ene-1,4-diol uses
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF-Cell
Coupling :
unconjugated
Clone number:
C9-B0
RRID:
AB_3068768
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing.Formula of 2-Hydroxyethyl methacrylate Aliquot store at -20℃ or -80℃.PMID:33604837 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
58 kDa
Positive control :
Hela, A549, HUVEC, rat testis tissue, human tonsil tissue, human liver cancer tissue, mouse brain tissue.