Product Name :
UBOX5 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
UIP5 UIP-5 UIP 5 RING finger protein 37 RNF37 U-box domain containing 5 U-box domain-containing protein 5 UBCE7IP5 ubiquitin conjugating enzyme 7 interacting protein 5 UBOX5 展开
Function :
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human UBOX5/RNF37 21-120/541
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep
Verify application:
WB, ELISA
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.Formula of cataCXium Pd G4 Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.XantPhos Pd G3 Chemscene When reconstituted in sterile pH 7.PMID:33419856 4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
59 KDa
Positive control :
Broadly expressed, with highest levels in skeletal muscle, kidney and pancreas. Present in acinar cells of the pancreas (at protein level).