Product Name :
2-Picolinic acid (CAS 98-98-6)

Synonym :
Pyridine-2-carboxylic acid

Application :

CAS:
98-98-6

Purity:
99%

Molecular Weight:
123.11

Formula :
C6H5NO2

Physical state:
Solid

solubility :
Soluble in glacial acetic acid, water (50 mg/ml), ethanol (63 mg/ml), and methanol. Insoluble in chloroform.

Shipping Condition :
Store at room temperature

Melting point:
139-142° C (lit.)

SMILES:
C1=CC=NC(=C1)C(=O)O

References:
:Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid. | Li, X., et al. 2013. Chem Commun (Camb). 49: 312-4. PMID: 23172107Synthesis, crystal structure, and thermal decomposition of the cobalt(II) complex with 2-picolinic acid. | Li, D. and Zhong, GQ. 2014. ScientificWorldJournal. 2014: 641608. PMID: 24578654Isolation of a 2-picolinic acid-assimilating bacterium and its proposed degradation pathway. | Zheng, C., et al. 2017. Bioresour Technol. 245: 681-688. PMID: 28917103One-step synthesis of Fe3PtPd(OH)2[Picolinic acid]8(H2O)4 hybrid nanorods: efficient and stable electrocatalyst for oxygen reduction reaction in alkaline solution. | Asiabi, H., et al. 2018. Sci Rep. 8: 15325. PMID: 30333559Metal-Free Decarboxylative Alkoxylation of 2-Picolinic Acid and Its Derivatives with Cyclic Ethers: One Step Construction of C-O and C-Cl Bonds. | Yu, X., et al. 2018. Org Lett. 20: 6780-6784. PMID: 30350643Synergistic Effect between Different Coordination Geometries of Lanthanides and Various Coordination Modes of 2-Picolinic Acid Ligands Tuning Three Types of Rare 3d-4f Heterometallic Tungstoantimonates. | Chen, Y., et al. 2018. Inorg Chem. 57: 15079-15092.89284-85-5 Order PMID: 30480437Zhizhu decoction alleviates slow transit constipation by regulating aryl hydrocarbon receptor through gut microbiota.4-Formylbenzenesulfonic acid web | Wen, Y.PMID:33595143 , et al. 2023. Pharm Biol. 61: 111-124. PMID: 36562308Tryptophan and Substance Abuse: Mechanisms and Impact. | Davidson, M., et al. 2023. Int J Mol Sci. 24: PMID: 36769059Design, Synthesis, Herbicidal Activity, and Structure-Activity Relationship Study of Novel 6-(5-Aryl-Substituted-1-Pyrazolyl)-2-Picolinic Acid as Potential Herbicides. | Feng, T., et al. 2023. Molecules. 28: PMID: 36771096Cocrystal of phloretin with isoniazid: preparation, characterization, and evaluation. | Lu, Z., et al. 2023. RSC Adv. 13: 10914-10922. PMID: 37033443Lipopolysaccharide-induced changes in the kynurenine pathway and symptoms of sickness behavior in humans. | Balter, LJ., et al. 2023. Psychoneuroendocrinology. 153: 106110. PMID: 37075653Expression and Characterization of 3,6-Dihydroxy-picolinic Acid Decarboxylase PicC of Bordetella bronchiseptica RB50. | Yuan, C., et al. 2023. Microorganisms. 11: PMID: 37110277Tryptophan intake, not always the more the better. | Hu, D., et al. 2023. Front Nutr. 10: 1140054. PMID: 37113297Determination of Picolinic Acid by HPLC Coupled With Postcolumn Photo Irradiation Using Zinc Acetate as a Fluorescent Derivatization Reagent. | Mawatari, KI., et al. 2023. Int J Tryptophan Res. 16: 11786469221146596. PMID: 37151811